Interested in this peptide?
Request more information and our team will get back to you within 2 business days.
What Is MGF?
MGF (Mechano Growth Factor, also known as IGF-1Ec) is a splice variant of the IGF-1 gene expressed in muscle tissue in response to mechanical stimulation (exercise) or damage. Unlike systemic IGF-1, MGF acts locally to activate satellite cells and promote muscle repair.
Key Characteristics
- Type: IGF-1 splice variant
- Trigger: Mechanical stress/muscle damage
- Action: Local muscle repair signaling
- Research variant: PEG-MGF (stabilized)
Mechanism of Action
- Released locally from damaged muscle
- Activates muscle satellite cells (stem cells)
- Promotes satellite cell proliferation
- Initiates muscle repair cascade
- Different E-peptide from systemic IGF-1
Research Interest
- Muscle regeneration after injury
- Muscular dystrophy research
- Age-related muscle loss (sarcopenia)
- Athletic recovery (research context)
Research Status
MGF is not approved for human use. PEG-MGF and other variants are research compounds only. Use in sports is prohibited. Human safety and efficacy data are lacking.
Summary
MGF represents the body's local response to muscle damage, distinct from systemic IGF-1 effects. It plays a key role in satellite cell activation and muscle regeneration, making it of interest in muscle repair research.